Brian E Lacy Selected Research

tegaserod (Zelnorm)

1/2022	Re-evaluation of the Cardiovascular Safety Profile of Tegaserod: A Review of the Clinical Data.
1/2021	Tegaserod for Irritable Bowel Syndrome With Constipation in Women Younger Than 65 Years Without Cardiovascular Disease: Pooled Analyses of 4 Controlled Trials.
10/2006	Systematic Review: FDA-Approved Prescription Medications for Adults With Constipation.
1/2002	Tegaserod: a new 5-HT4 agonist.

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Brian E Lacy Research Topics

Disease

24	Constipation 01/2022 - 01/2002
22	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 01/2022 - 01/2002
13	Diarrhea 01/2021 - 05/2012
12	Abdominal Pain (Pain, Abdominal) 01/2021 - 01/2002
11	Dyspepsia (Indigestion) 03/2022 - 05/2012
10	Gastroparesis 11/2021 - 06/2002
9	Gastroesophageal Reflux (GERD) 01/2019 - 07/2005
7	Nausea 01/2021 - 07/2009
4	Esophageal Achalasia (Megaesophagus) 11/2021 - 04/2008
4	Pancreatitis 01/2021 - 04/2016
3	Obesity 01/2022 - 10/2020
3	Vomiting 01/2021 - 07/2009
3	Pain (Aches) 01/2021 - 01/2016
3	Deglutition Disorders (Dysphagia) 10/2020 - 01/2002
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022 - 01/2021
2	Feeding and Eating Disorders (Eating Disorder) 01/2022 - 01/2021
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2021
2	Weight Loss (Weight Reduction) 01/2022 - 01/2021
2	Esophageal Motility Disorders (Nutcracker Esophagus) 10/2020 - 05/2008
2	Diffuse Esophageal Spasm (Esophageal Spasm) 01/2019 - 04/2008
2	Ataxia (Dyssynergia) 12/2015 - 08/2015
2	Ulcer 08/2015 - 02/2002
2	Muscle Spasticity (Spastic) 07/2015 - 04/2008
2	Chest Pain (Chest Pains) 05/2011 - 10/2009
1	Hyperlipidemias (Hyperlipidemia) 01/2022
1	Hypertension (High Blood Pressure) 01/2022
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 12/2021
1	Tardive Dyskinesia 11/2021
1	Eosinophilic Esophagitis 11/2021
1	Thymoma (Thymic Carcinoma) 11/2021
1	Esophagitis 11/2021
1	Inflammation (Inflammations) 11/2020
1	Opioid-Induced Constipation 01/2020

Drug/Important Bio-Agent (IBA)

8	eluxadolineIBA 01/2021 - 01/2016
7	Antidepressive Agents (Antidepressants)IBA 01/2019 - 05/2012
6	linaclotideIBA 01/2022 - 10/2012
6	Lubiprostone FDA Link 04/2015 - 07/2006
5	Opioid Analgesics (Opioids)IBA 11/2021 - 07/2015
5	alosetron (Lotronex)FDA Link 10/2018 - 11/2013
5	AcidsIBA 01/2018 - 02/2002
4	tegaserod (Zelnorm)FDA Link 01/2022 - 01/2002
4	Rifaximin (L 105)FDA Link 01/2021 - 04/2015
4	acceleratory factor from growth hormone (AcG)IBA 01/2021 - 01/2017
4	Loperamide (Imodium)FDA LinkGeneric 10/2018 - 04/2015
4	Botulinum Toxins (Botulinum Toxin)IBA 04/2008 - 01/2002
3	Metoclopramide (Reglan)FDA LinkGeneric 11/2021 - 01/2017
3	Pharmaceutical PreparationsIBA 01/2021 - 10/2012
3	Proton Pump InhibitorsIBA 01/2018 - 07/2005
3	Amitriptyline (Elavil)FDA LinkGeneric 06/2017 - 05/2012
3	Opioid Receptors (Opioid Receptor)IBA 01/2017 - 04/2015
3	Capsules (Microcapsules)IBA 09/2011 - 07/2009
3	Chloride Channels (Chloride Channel)IBA 01/2009 - 04/2007
2	caraway oilIBA 03/2022 - 01/2019
2	Menthol FDA Link 03/2022 - 01/2019
2	Serotonin 5-HT4 Receptor AgonistsIBA 11/2021 - 12/2009
2	Parasympatholytics (Antispasmodics)IBA 01/2021 - 04/2015
2	Scopolamine (Hyoscine)FDA Link 01/2021 - 08/2013
2	Guanylate Cyclase (Guanylyl Cyclase)IBA 01/2021 - 01/2018
2	goblet cell silencer inhibitorIBA 11/2020 - 01/2019
2	Dietary Fiber FDA Link 01/2020 - 04/2015
2	Anti-Bacterial Agents (Antibiotics)IBA 11/2018 - 04/2015
2	PrebioticsIBA 11/2018 - 10/2014
2	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA 10/2018 - 12/2014
2	Lipase (Acid Lipase)FDA Link 01/2017 - 04/2016
2	AntralIBA 12/2015 - 08/2015
2	Escitalopram FDA Link 08/2015 - 05/2012
2	Serotonin (5 Hydroxytryptamine)IBA 04/2015 - 12/2009
2	BariumIBA 07/2010 - 07/2005
1	5-HT4 Serotonin ReceptorsIBA 01/2022
1	LaxativesIBA 01/2022
1	Phenobarbital (Luminal)FDA Link 12/2021
1	Neurokinin-1 Receptors (Neurokinin 1 Receptor)IBA 11/2021
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 11/2021
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 11/2021
1	Metformin (Glucophage)FDA LinkGeneric 11/2021
1	Type A Botulinum Toxins (Botox)FDA Link 11/2021
1	Dicyclomine (Bentyl)FDA LinkGeneric 01/2021
1	mebeverineIBA 01/2021
1	alverineIBA 01/2021
1	pinaveriumIBA 01/2021
1	TrimebutineIBA 01/2021
1	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2021
1	HyoscyamineIBA 01/2021
1	Chloride Channel AgonistsIBA 01/2021
1	SecretagoguesIBA 01/2020
1	Opiate AlkaloidsIBA 01/2020

Therapy/Procedure

25	Therapeutics 03/2022 - 03/2004
2	Myotomy 11/2021 - 11/2020
2	Pyloromyotomy 11/2021 - 11/2020
2	Diet Therapy (Therapy, Diet) 01/2021 - 01/2016
2	Gastric Bypass (Roux-en-Y Gastric Bypass) 10/2020 - 02/2002
2	Fundoplication 01/2018 - 12/2016
1	Off-Label Use 01/2022
1	Contraindications 01/2021
1	Drug Therapy (Chemotherapy) 01/2021
1	Gastrectomy 10/2020
1	Bariatric Surgery 10/2020
1	Colectomy 01/2020
1	Microspheres (Microsphere) 01/2019
1	Pain Management 01/2019